Family History of CHD Is Associated With Severe CAC in South Asians: Comparing the MASALA and MESA Studies.
نویسندگان
چکیده
*Parag H. Joshi, MD, MHS Michael J. Blaha, MD, MPH Matthew J. Budoff, MD Michael D. Miedema, MD, MPH Robyn L. McClelland, PhD Joao A.C. Lima, MD Arthur S. Agatston, MD Ron Blankstein, MD Roger S. Blumenthal, MD Khurram Nasir, MD, MPH *Department of Medicine Division of Cardiology University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard, #E5-730F Dallas, Texas 75390-8830 E-mail: [email protected]
منابع مشابه
Inflammation and coronary artery calcification in South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) study.
BACKGROUND AND AIMS Inflammatory biomarkers and adipocytokines (IBA) may contribute to atherosclerosis by promoting vascular inflammation. The association between IBA and coronary artery calcium (CAC), a marker of subclinical atherosclerosis, is not well defined in South Asians (SA). We hypothesized that IBA (high sensitivity C-reactive protein [hsCRP], tumor necrosis factor alpha [TNF-α], adip...
متن کاملFamily history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA).
BACKGROUND A family history of premature coronary heart disease (CHD) is a known risk factor for CHD events. The purpose of this study was to assess the strength of the association between a family history of premature CHD and coronary artery calcification (CAC) in a multiethnic cohort of asymptomatic individuals. We also sought to determine whether individuals with a reported family history of...
متن کاملCardiovascular health metrics among South Asian adults in the United States: Prevalence and associations with subclinical atherosclerosis.
South Asians, a fast growing ethnic group in the US, have an increased risk for cardiovascular disease compared to the general population. We examined the prevalence and distribution of the American Heart Association's Life's Simple 7 cardiovascular health (CVH) metrics using data from Mediators of Atherosclerosis in South Asians Living in America (MASALA) study, and cross-sectional association...
متن کاملUnderstanding the High Prevalence of Diabetes in U.S. South Asians Compared With Four Racial/Ethnic Groups: The MASALA and MESA Studies
OBJECTIVE We compared South Asians with four other racial/ethnic groups in the U.S. to determine whether sociodemographic, lifestyle, or metabolic factors could explain the higher diabetes prevalence and whether insulin resistance and β-cell dysfunction occurred at younger ages and/or lower adiposity levels compared with other groups. RESEARCH DESIGN AND METHODS We performed a cross-sectional...
متن کاملMediators of Atherosclerosis in South Asians Living in America (MASALA) study: objectives, methods, and cohort description.
BACKGROUND South Asians (individuals from India, Pakistan, Bangladesh, Nepal, and Sri Lanka) have high rates of cardiovascular disease (CVD) that cannot be explained by traditional risk factors. There are few prospective cohort studies investigating antecedents of CVD in South Asians. OBJECTIVES The Mediators of Atherosclerosis in South Asians Living in America (MASALA) study is investigating...
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ورودعنوان ژورنال:
- JACC. Cardiovascular imaging
دوره 10 8 شماره
صفحات -
تاریخ انتشار 2017